DEET-Based Insect Repellents

🔴 HIGH — Dangerous

Why is it risky?

N,N-diethyl-meta-toluamide (DEET), the active ingredient in most human mosquito and tick repellents, causes neurotoxicity in cats via cholinesterase inhibition. Cats cannot efficiently metabolize DEET through the same hepatic pathways available to humans and dogs. Exposure most often occurs when cats contact skin or surfaces where repellent was applied, or when owners incorrectly apply human repellents to cats attempting to prevent parasites.

Affected Systems

Digestive · Nervous

Symptoms

Salivation, vomiting, tremors, ataxia, seizures. Severity correlates with DEET concentration and exposure amount.

What To Do

Contact vet or poison control immediately. If product is on fur: wash thoroughly with mild soap and water. Anticonvulsant and supportive care for severe cases.

Notes

Never apply human insect repellents to cats, no DEET-based product is licensed for feline use. Cats can be exposed by grooming owners who have applied repellent to arms or legs, wash applied areas before close cat contact. For tick and mosquito prevention in cats, use veterinary-licensed products (fipronil, selamectin).

Sources

→ ASPCA Animal Poison Control Center — aspca.org

→ Merck Veterinary Manual — merckvetmanual.com

→ Pet Poison Helpline — petpoisonhelpline.com

⚠️ Disclaimer: The information on SafeCatBase is for educational purposes only and does not replace professional veterinary advice. Always consult a qualified veterinarian for any health concerns about your cat.
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