Why is it risky?
Phenolic compounds, chloroxylenol (Dettol), phenol, and related derivatives, are highly hepatotoxic and nephrotoxic to cats. Cats are deficient in glucuronyl transferase, the primary enzyme for metabolizing phenols in other mammals. Compounds that humans and dogs process efficiently accumulate to toxic levels in cats. Exposure through paw contact with treated floors, followed by grooming, is the most common route.
Affected Systems
Nervous · Kidneys · Liver · Skin
Symptoms
Drooling, vomiting, ataxia, muscle weakness, respiratory depression, jaundice (yellowing of gums and eyes), seizures, coma.
What To Do
Emergency vet. If paw contact: wash paws immediately with water and mild dish soap. Do NOT induce vomiting. Liver function testing required. IV fluids and liver-protective agents are the primary treatment.
Notes
Dettol turns milky white when diluted in water, this is the characteristic indicator. Despite being marketed for household hygiene, it should not be used on any surface cats can access while wet. Safer cat-compatible alternatives for surface disinfection: accelerated hydrogen peroxide products (F10, Rescue) or diluted sodium hypochlorite applied to surfaces that are then thoroughly rinsed and fully dried before cat access.
Sources
→ ASPCA Animal Poison Control Center — aspca.org
→ Merck Veterinary Manual — merckvetmanual.com/toxicology
→ Pet Poison Helpline — petpoisonhelpline.com